Topic description and stories

DNA jigsaw with pieces missing

Scientists identify genes linked to DNA damage and human disease

16 Feb 2024

Cambridge scientists have identified more than one hundred key genes linked to DNA damage through systematic screening of nearly 1,000 genetically...

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Older man skydiving

Ageing: can we add more life to our years?

20 Dec 2023

Research advances at the University of Cambridge mean that the eternal quest to reverse the march of time may soon become a reality.

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Alzheimers disease. Computer illustration of amyloid plaques amongst neurons.

AI-driven techniques reveal new targets for drug discovery

27 Sep 2023

Researchers have developed a method to identify new targets for human disease, including neurodegenerative conditions such as Alzheimer’s disease.

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Corpus callosum, left-right connections, in a Parkinson's brain

Slow-moving shell of water can make Parkinson’s proteins ‘stickier’

15 Nov 2022

Water – which makes up the majority of every cell in the body – plays a key role in how proteins, including those associated with Parkinson’s disease...

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Neuron

Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells

20 Jun 2022

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways...

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Mammalian cell stained with fluorescence polymeric thermometers and falsely-coloured based on temperature gradients.

Alzheimer’s disease causes cells to overheat and ‘fry like eggs’

31 May 2022

Researchers have shown that aggregation of amyloid-beta, one of two key proteins implicated in Alzheimer’s disease, causes cells to overheat and ‘fry...

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SumaLateral Whole Brain Image

Scientists identify the cause of Alzheimer’s progression in the brain

29 Oct 2021

For the first time, researchers have used human data to quantify the speed of different processes that lead to Alzheimer’s disease and found that it...

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Spatially oriented neurons (mouse brain)

Scientists reverse age-related memory loss in mice

22 Jul 2021

Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of...

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Screening for glaucoma

Gene therapy technique shows potential for repairing damage caused by glaucoma and dementia

31 Mar 2021

Scientists at the University of Cambridge have shown in animal studies that gene therapy may help repair some of the damage caused in chronic...

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Brain Chip

Function identified of ‘mystery protein’ that kills healthy brain cells of people with Parkinson’s

10 Feb 2021

Scientists have made a ‘vital step’ towards understanding the origins of Parkinson’s disease – the fastest growing neurological condition in the...

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Beta-Amyloid Plaques and Tau in the Brain

Following the hops of disordered proteins could lead to future treatments of Alzheimer’s disease

14 Jan 2021

Study shows how to determine the elusive motions of proteins that remain disordered.

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