Grandmother and grandchildren

Inherited ‘memory’ of nutrition during pregnancy may be limited to children and grandchildren

10 Jul 2014

When a pregnant mother is undernourished, her child is at a greater than average risk of developing obesity and type 2 diabetes, in part due to so-called ‘epigenetic’ effects. A new study in mice demonstrates that this ‘memory’ of nutrition during pregnancy can be passed through sperm of male offspring to the next generation, increasing risk of disease for her grandchildren as well – in other words, to adapt an old maxim, ‘you are what your grandmother ate’.

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NICE approves MS drug developed by University of Cambridge researchers

28 May 2014

A new drug based on decades of research at the University of Cambridge has today been approved by the National Institute for Health and Care Excellence (NICE) for use in people with relapsing-remitting multiple sclerosis. Clinical trials have shown that Alemtuzumab, marketed under the name Lemtrada, reduces disease activity, limits the accumulation of further disability over time and may even allow some existing damage to recover.

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Functional nerve cells from skin cells

22 May 2014

Research will make the study of diseases such as Parkinson’s and Alzheimer’s easier, and could lead to personalised therapies for a variety of neurodegenerative disorders.

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Mini-livers show promise to reduce animal use in science

26 Feb 2014

Cambridge research that has for the first time successfully grown “mini-livers” from adult mouse stem cells has won the UK’s international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of animals in science (the 3Rs).

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