When a pregnant mother is undernourished, her child is at a greater than average risk of developing obesity and type 2 diabetes, in part due to so-called ‘epigenetic’ effects. A new study in mice demonstrates that this ‘memory’ of nutrition during pregnancy can be passed through sperm of male offspring to the next generation, increasing risk of disease for her grandchildren as well – in other words, to adapt an old maxim, ‘you are what your grandmother ate’.
A new drug based on decades of research at the University of Cambridge has today been approved by the National Institute for Health and Care Excellence (NICE) for use in people with relapsing-remitting multiple sclerosis. Clinical trials have shown that Alemtuzumab, marketed under the name Lemtrada, reduces disease activity, limits the accumulation of further disability over time and may even allow some existing damage to recover.
Study illustrates “high conservation potential” of vaccines for endangered wild primates devastated by viral disease, but highlights need for access to captive chimpanzees so vaccines can be trialled before being administered in the wild.
A new technique developed at the University of Cambridge allows researchers to identify clusters of proteins on immune cells which are key to fighting off the body’s invaders.
Molecular ‘fingerprint’ for tissue taken from first isotope-enriched mouse has huge potential for scientific breakthroughs, as well as improved medical implants. Earliest research based on data has already revealed that a molecule thought to exist for repairing DNA may also in fact trigger bone formation.
The University of Cambridge announces today that it has signed the Concordat on Openness on Animal Research in the UK, joining over seventy organisations including academia, industry, funders and charities.
New research shows that male jays are able to disengage from their own current desires to feed their female partner food that she wants.
Like other social animals, baboons learn from each other about which foods are best to eat. Now, researchers at Cambridge have found that how well they learn from others depends on their personality, bold or anxious baboons learning more than those who are shy or laid back.
Cambridge research that has for the first time successfully grown “mini-livers” from adult mouse stem cells has won the UK’s international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of animals in science (the 3Rs).