Topic description and stories

Mycobacterium tuberculosis

Gene discovery provides clues to how TB may evade the immune system

16 Mar 2015

The largest genetic study of tuberculosis (TB) susceptibility to date has led to a potentially important new insight into how the pathogen manages to...

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DNA (cropped)

Human genome includes 'foreign' genes not from our ancestors

12 Mar 2015

Many animals, including humans, acquired essential ‘foreign’ genes from microorganisms co-habiting their environment in ancient times, according to...

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Fifteen new breast cancer genetic risk ‘hot-spots’ revealed

09 Mar 2015

Scientists have discovered 15 previously unknown genetic ‘hot-spots’ that can increase a woman’s risk of developing breast cancer, according to...

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Red blood cells (illustration)

Order matters: sequence of genetic mutations determines how cancer behaves

11 Feb 2015

The order in which genetic mutations are acquired determines how an individual cancer behaves, according to research from the University of Cambridge...

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Structure of the mariner transpososome.

Why jumping genes don’t send us into meltdown

20 Jun 2013

Scientists have explained, for the first time, how transposition is regulated in the bodies of humans and other living organisms.

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Sleeping sickness by stealth

04 Feb 2013

New research is helping to unveil how the parasite that causes sleeping sickness uses stealth tactics to escape detection by the human immune system.

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DNA

Genetic roulette in a new world

17 Aug 2012

Dr Robin Hesketh, Senior Lecturer in the Department of Biochemistry and author of Betrayed by Nature, explains how advances in inexpensive, rapid...

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Replacement of a faulty gene by gene therapy

Clean correction of a patient’s genetic mutation

13 Oct 2011

New gene therapy methods accurately correct mutation in patient’s stem cells, bringing personalized cell therapies one step closer.

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Beakers

Scientists demonstrate potential new treatment for most common form of infant leukaemia

03 Oct 2011

New drug could treat mixed-lineage leukaemia (MLL).

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Beakers

Gene that controls chronic pain identified

12 Sep 2011

Research lays groundwork for the development of new, targeted pain medications.

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Human liver cells

Consortium finds chronic liver cirrhosis clues

21 Mar 2011

Researchers have provided new clues into the genetics underlying a chronic form of liver disease, called primary biliary cirrhosis, which can lead to...

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Foetus

Immune interaction optimises foetal nourishment during pregnancy

08 Feb 2011

Paternal genes advise maternal immune cells on how to build the best womb for developing foetuses, researchers have found.

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