Topic description and stories

Artist's impression of Crohn's disease

Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes

22 Feb 2024

A large-scale clinical trial of treatment strategies for Crohn’s disease has shown that offering early advanced therapy to all patients straight...

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Emerging intestinal villi with stem cells (green) supporting their growth

Gut research identifies key cellular changes associated with childhood-onset Crohn’s Disease

07 Dec 2020

Scientists have tracked the very early stages of human foetal gut development in incredible detail, and found specific cell functions that appear to...

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Dr James Lee

New prognostic test could enable personalised treatment of inflammatory bowel disease

03 May 2019

Scientists at the University of Cambridge have developed a new test that can reliably predict the future course of inflammatory bowel disease in...

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DNA

Crohn’s disease risk and prognosis determined by different genes, study finds

09 Jan 2017

Researchers have identified a series of genetic variants that affect the severity of Crohn’s disease, an inflammatory bowel disease – but...

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Histopathological image of the active stage of ulcerative colitis. Endoscopic biopsy. Hematoxylin & eosin stain.

Scientists explore using stem cells to treat inflammatory bowel disease

18 Oct 2013

Research paves way for new therapies for ulcerative colitis and Crohn's disease

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Gene variant linked to prognosis in inflammatory diseases

04 Oct 2013

Researchers have identified a gene that is linked to long term disease outcome in Crohn's disease, a common inflammatory bowel disorder, and...

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Specialised intestinal cells cause some cases of Crohn’s disease

02 Oct 2013

Researchers discover that the cells play a major role in inflammation which underlies Crohn’s disease in small intestine.

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