Tendon problems can be very painful and often have few effective treatments. A team of Cambridge researchers are hoping to find a more effective way of relieving the symptoms of tendon problems with the help of a research grant by the Arthritis Research Campaign (arc).

Tendinopathy is a common condition, which occurs in many people with arthritis. Dr Graham Riley, head of soft tissue research, based at Addenbrooke's Hospital and his team have been awarded a grant of almost £120,000 by arc to find better ways to treat the condition.

Tendinopathy is caused when the structure and composition of the tendon degenerates, leading to weakness and pain. The cause of tendon degeneration is not known, although the age and physical activities of a patient are both risk factors. Patients can develop it slowly over many months, or suddenly from a tendon rupture.

Both conditions are difficult to treat, and current forms of treatment, such as rest, physiotherapy and anti-inflammatory drugs are often ineffective. Surgery is usually a last resort, but in many cases it doesn’t give a satisfactory result.

Dr Riley and his team are investigating the possibility that substances called ‘tachykinins’ - in particular a type of tachykinin called substance P - which are produced by nerve endings in the tissue, play a part in the development of tendinopathy.

Dr Graham Riley, head of soft tissue research, said:

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