Lupski appointed Professor of Medical Genetics

Professor Lupski is currently the Cullen Professor of Molecular and Human Genetics, and Professor of Pediatrics, Baylor College of Medicine in Houston, Texas. Professor Lupski completed a sabbatical at the Wellcome Trust Sanger Institute last academic year where he studied mouse genetics and genomics.

“The Addenbrooke’s Hospital complex and Clinical School, in the context of the Cambridge academic environment, offer an unprecedented opportunity to catalyze future developments in medical and human genetics during the post-genomic era. In this city where molecular genetics was born and nurtured we have the opportunity to apply the wisdom of the discipline that comes with age to the benefit of our patients and families. These are incredibly exciting times for genetics and medicine!” says Lupski.

At the Baylor College of Medicine, his laboratory determines molecular mechanisms for disease using molecular biological, genomic, and human genetic approaches to investigate clinical phenotypes. His laboratory has delineated the concept of “genomic disorders” and established the critical role of gene dosage in conveying human disease phenotypes. An increasing number of human diseases are recognized to result from recurrent DNA rearrangements involving unstable genomic regions and have thus been classified as genomic disorders.