A team of researchers from across Cambridge has shed light on a long-standing debate about why the immune system weakens with age. Their findings, published today in Science, show that immune cells in older tissues lack coordination and exhibit much more variability in gene expression (activity) compared with their younger counterparts.
Scientists have discovered a group of materials which could pave the way for a new generation of high-efficiency lighting, solving a quandary which has inhibited the performance of display technology for decades. The development of energy saving concepts in display and lighting applications is a major focus of research, since a fifth of the world’s electricity is used for generating light.
OCD can be a devastating condition: therapy and medication often doesn’t work, leaving many people unable to hold down a job or a relationship – or even to leave their house. In our series of films, science writer David Adam looks at how research at Cambridge using animals helps us understand what is happening in the brain – and may lead to better treatments.
‘Big data’ study finds that children from families with limited education have strongest long-term response to teacher encouragement, and are more likely to progress to university as a result.
A genetic trawl through the DNA of almost 100,000 people, including 17,000 patients with the most common type of ovarian cancer, has identified 12 new genetic variants that increase risk of developing the disease and confirmed the association of 18 of the previously published variants.
Scientists at the University of Cambridge and the Wellcome Trust Sanger Institute have created a new technique that simplifies the production of human brain and muscle cells - allowing millions of functional cells to be generated in just a few days. The results published today in Stem Cell Reports open the door to producing a diversity of new cell types that could not be made before in order to study disease.
Moderate drinking is associated with a lower risk of several, but not all, cardiovascular diseases, according to a large study of UK adults led by researchers at the University of Cambridge and University College London published today in The BMJ.
New archaeological analysis suggests people of Western Roman Empire switched between Hunnic nomadism and settled farming over a lifetime. Findings may be evidence of tribal encroachment that undermined Roman Empire during 5th century AD, contributing to its fall.
More than a century of theory about the evolutionary history of dinosaurs has been turned on its head following the publication of new research from scientists at the University of Cambridge and Natural History Museum in London. Their work suggests that the family groupings need to be rearranged, re-defined and re-named and also that dinosaurs may have originated in the northern hemisphere rather than the southern, as current thinking goes.
Infections during pregnancy may interfere with key genes associated with autism and prenatal brain development21 Mar 2017
If a mother picks up an infection during pregnancy, her immune system will kick into action to clear the infection – but this self-defence mechanism may also have a small influence how her child’s brain develops in the womb, in ways that are similar to how the brain develops in autism spectrum disorders. Now, an international team of researchers has shown why this may be the case, in a study using rodents to model infection during pregnancy.