Opinion: How epigenetics may help us slow down the ageing clock

12 May 2017

Why do we age when we get older? Epigenetics may hold the answer – but could it one day help us turn back the clock? Professor Wolf Reik from the Department of Physiology, Development and Neuroscience at the University of Cambridge and Dr Oliver Stegle from the European Bioinformatics Institute look at the ‘epigenetic clock’ in The Conversation.

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New stem cell method produces millions of human brain and muscle cells in days

23 Mar 2017

Scientists at the University of Cambridge and the Wellcome Trust Sanger Institute have created a new technique that simplifies the production of human brain and muscle cells - allowing millions of functional cells to be generated in just a few days. The results published today in Stem Cell Reports open the door to producing a diversity of new cell types that could not be made before in order to study disease.

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'The Iron Lady' and the paradox of treating anaemia

03 Feb 2017

Iron deficiency can be fatal. But in countries where patients are also likely to have other serious diseases, so too can the iron supplements used to treat it. Nearly 12 years ago, Dora Pereira – sometimes referred to as ‘The Iron Lady’ – was part of the team who had an idea for a new supplement. She now leads its clinical trial in The Gambia.

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Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

29 Nov 2016

Researchers from the Wellcome Trust Sanger Institute and the University of Cambridge have created sOPTiKO, a more efficient and enhanced inducible CRISPR genome editing platform. Today, in the journal Development, they describe how the freely available single-step system works in every cell in the body and at every stage of development. This new approach will aid researchers in developmental biology, tissue regeneration and cancer.

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