Topic description and stories

DNA

Researchers call for greater awareness of unintended consequences of CRISPR gene editing

12 Apr 2021

CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos, researchers have revealed. This...

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Women in STEM: Dr Alexis Braun

26 Sep 2019

Dr Alexis Braun is a postdoctoral researcher in the Department of Genetics. Here, she tells us about the importance of mentors, how her research...

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Scissors cut metal

Genome-editing tool could increase cancer risk in cells, say researchers

11 Jun 2018

More research needs to be done to understand whether CRISPR-Cas9 – molecular ‘scissors’ that make gene editing a possibility – may inadvertently...

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Genome editing reveals role of gene important for human embryo development

20 Sep 2017

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development. This is the...

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Snip, snip, cure: correcting defects in the genetic blueprint

14 Jul 2017

Gene editing using ‘molecular scissors’ that snip out and replace faulty DNA could provide an almost unimaginable future for some patients: a...

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Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

29 Nov 2016

Researchers from the Wellcome Trust Sanger Institute and the University of Cambridge have created sOPTiKO, a more efficient and enhanced inducible...

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