New innovation hub aims to take a 'moon shot' at cystic fibrosis

18 Apr 2018

Almost 30 years on from the discovery of the genetic defect that causes cystic fibrosis, treatment options are still limited and growing antibiotic resistance presents a grave threat. Now, a team of researchers from across Cambridge, in a major new centre supported by the Cystic Fibrosis Trust, hopes to turn fortunes around.

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The body in miniature

20 Mar 2018

The past few years has seen an explosion in the number of studies using organoids – so-called ‘mini organs’. While they can help scientists understand human biology and disease, some in the field have questioned their usefulness. But as the field matures, we could see their increasing use in personalised and regenerative medicine.

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‘Mini liver tumours’ created in a dish for the first time

16 Nov 2017

Scientists have created mini biological models of human primary liver cancers, known as organoids, in the lab for the first time. In a paper published in Nature Medicine, the tiny laboratory models of tumours were used to identify a new drug that could potentially treat certain types of liver cancer.

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Scientists reveal the beautiful simplicity underlying branching patterns in tissue

21 Sep 2017

In the centenary year of the publication of a seminal treatise on the physical and mathematical principles underpinning nature – On Growth and Form by D’Arcy Wentworth Thompson – a Cambridge physicist has led a study describing an elegantly simple solution to a puzzle that has taxed biologists for centuries: how complex branching patterns of tissues arise. 

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