An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation long enough to respond to and stop virus infection.
A new diagnostic test developed from research at the Universities of Cambridge and Dundee has been launched with the aim of helping eliminate the disease known as African sleeping sickness.
Leprosy hijacks our immune system, turning an important repair mechanism into one that causes potentially irreparable damage to our nerve cells, according to new research that uses zebrafish to study the disease. As such, the disease may share common characteristics with conditions such as multiple sclerosis.
An innovative new study takes a network theory approach to targeted treatment in rural Africa, and finds that a simple algorithm may be more effective than current policies, as well as easier to deploy, when it comes to preventing disease spread – by finding those with “most connections to sick people”.
An on-the-spot, low-cost diagnostic test for leptospirosis (Weil's disease), a bacterial infection recognised as a neglected disease by the World Health Organization, could save lives in developing countries where there is little or no access to medical pathology laboratories and specialist technicians.
Scientists have uncovered why Zika virus may specifically target neural stem cells in the developing brain, potentially leading to microcephaly – a potentially serious birth defect where the brain fails to develop properly, leading to a smaller head.
Infections during pregnancy may interfere with key genes associated with autism and prenatal brain development21 Mar 2017
If a mother picks up an infection during pregnancy, her immune system will kick into action to clear the infection – but this self-defence mechanism may also have a small influence how her child’s brain develops in the womb, in ways that are similar to how the brain develops in autism spectrum disorders. Now, an international team of researchers has shown why this may be the case, in a study using rodents to model infection during pregnancy.
We are still part-virus, writes Edward Emmott, Research Associate in Virology, for The Conversation. Human DNA plays host to a range of different viruses. And this could help explain why it has been so difficult to develop effective antiviral drugs.
Working in a lab as a basic scientist can often seem far removed from the real world. A year since the World Health Organization declared the Ebola outbreak over, one researcher tells how the skills he learned working in a lab in Cambridge turned out to be surprisingly useful in fighting one of the most terrifying disease outbreaks of recent times.
Writing for The Conversation, Edward Emmott, Research Associate in Virology explores why this notorious virus can cause the NHS such difficulty.