A common class of chemicals found everywhere from car exhausts, smoke, building materials and furniture to cosmetics and shampoos could increase cancer risk because of their ability to break down the repair mechanisms that prevent faults in our genes, according to a study published today in the journal Cell.
Study identifies hundreds of genes that influence timing of puberty and alter risk of several cancers24 Apr 2017
The largest genomic analysis of puberty timing in men and women conducted to date has identified 389 genetic signals associated with puberty timing, four times the number that were previously known.
A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects in the mice and one is already licensed for use in humans, so is ready for clinical trials.
The University of Cambridge has been announced as one of the centres that will form the UK Dementia Research Institute (UK DRI) alongside Cardiff University, the University of Edinburgh, Imperial College London and King’s College London.
Scientists at the University of Cambridge have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture. These organoids, as they are known, could provide new insights into the early stages of pregnancy and conditions such as endometriosis, a painful condition that affects as many as two million women in the UK.
Scientists have determined the first 3D structures of intact mammalian genomes from individual cells, showing how the DNA from all the chromosomes intricately folds to fit together inside the cell nuclei.
Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge. The study, published today in Translational Psychiatry, raises hopes that there may be a biomarker – a biological measure of addiction – that could be used as a target for future treatments.
Iron deficiency can be fatal. But in countries where patients are also likely to have other serious diseases, so too can the iron supplements used to treat it. Nearly 12 years ago, Dora Pereira – sometimes referred to as ‘The Iron Lady’ – was part of the team who had an idea for a new supplement. She now leads its clinical trial in The Gambia.
Modafinil, a drug used to treat narcolepsy – excessive daytime sleepiness – can improve memory in patients recovering from depression, according to new research from the University of Cambridge. The findings, published today in the journal Biological Psychiatry: CNNI, result from a randomised, double-blind, placebo-controlled study and offer hope of a treatment for some of the cognitive symptoms of depression.
Working in a lab as a basic scientist can often seem far removed from the real world. A year since the World Health Organization declared the Ebola outbreak over, one researcher tells how the skills he learned working in a lab in Cambridge turned out to be surprisingly useful in fighting one of the most terrifying disease outbreaks of recent times.