Gene editing using ‘molecular scissors’ that snip out and replace faulty DNA could provide an almost unimaginable future for some patients: a complete cure. Cambridge researchers are working towards making the technology cheap and safe, as well as examining the ethical and legal issues surrounding one of the most exciting medical advances of recent times.
DNA sequencing has defined a new genetic disorder that affects movement, enabling patients with dystonia — a disabling condition that affects voluntary movement — to be targeted for treatment that brings remarkable improvements, including restoring independent walking.
New research dates plague back to the early Bronze Age, showing it had been endemic in humans across Eurasia for millennia prior to first recorded global outbreak, and that ancestral plague mutated into its bubonic, flea-borne form between the 2nd and 1st millennium BC.
The Cambridge Animal Alphabet series celebrates Cambridge's connections with animals through literature, art, science and society. Here, T is for Tasmanian Devil and the researchers studying the transmissable cancer that threatens these marsupials with extinction.
DNA from 4,500-year-old Ethiopian skull reveals a large migratory wave of West Eurasians into the Horn of Africa around 3,000 years ago had a genetic impact on modern populations across East Africa.
One of the world’s leading childhood brain tumour experts, Professor Richard Gilbertson, has been appointed as Li Ka Shing Chair of Oncology in Cambridge and Director of the Cambridge Cancer Centre. He will take up his appointment in August.
Dr Frederick Sanger, recognised by many as the “father of genomics”, died yesterday at the age of 95. The founding member of the MRC Laboratory of Molecular Biology in Cambridge, and the person after whom the Sanger Institute is named, he was known as an extremely modest and self-effacing man whose innumerable scientific contributions have had an extraordinary impact on molecular biology.