A small molecule that can turn short-lived ‘killer T-cells’ into long-lived, renewable cells that can last in the body for a longer period of time, activating when necessary to destroy tumour cells, could help make cell-based immunotherapy a realistic prospect to treat cancer.
Cambridge spin-out Carrick Therapeutics raises $95 million in funding, representing the largest-ever early stage investment in a UK university spin-out company.
Researchers have identified the role that a four-stranded version of DNA may play in the role of cancer progression, and suggest that it may be used to develop new targeted cancer therapies.
Tailored, targeted treatment for patients with oesophageal cancer could be developed after scientists discovered that the disease can be classified into three different subtypes
A study of 3.9 million adults published today in The Lancet has found that being overweight or obese is associated with an increased risk of premature death. The risks of coronary heart disease, stroke, respiratory disease and cancer are all increased. Overall, the excess risk of premature death (before age 70) among those who are overweight or obese is about three times as great in men as in women.
Tumours kill off surrounding cells to make room to grow, according to new research from the University of Cambridge. Although the study was carried out using fruit flies, its findings suggest that drugs to prevent, rather than encourage, cell death might be effective at fighting cancer – contrary to how many of the current chemotherapy drugs work.
Transmissible cancers – cancers which can spread between individuals by the transfer of living cancer cells – are believed to arise extremely rarely in nature. One of the few known transmissible cancers causes facial tumours in Tasmanian devils, and is threatening this species with extinction. Today, scientists report the discovery of a second transmissible cancer in Tasmanian devils.
The Cambridge Animal Alphabet series celebrates Cambridge's connections with animals through literature, art, science and society. Here, T is for Tasmanian Devil and the researchers studying the transmissable cancer that threatens these marsupials with extinction.
An international study of nearly 70,000 women has identified more than forty regions of the human genome that are involved in governing at what age a woman goes through menopause. The study, led by scientists at the Universities of Cambridge and Exeter, found that two thirds of those regions contain genes that act to keep DNA healthy, by repairing the small damages that can accumulate with age.