Distinguished members of the University of Cambridge have been named in the 2017 New Year Honours list, announced today. Professor Ottoline Leyser and Professor Shankar Balasubramanian and Professor John Pyle are among those who have been recognised for their contributions to society.
Researchers have identified the role that a four-stranded version of DNA may play in the role of cancer progression, and suggest that it may be used to develop new targeted cancer therapies.
A rare DNA base, previously thought to be a temporary modification, has been shown to be stable in mammalian DNA, suggesting that it plays a key role in cellular function.
A trawl through a library of more than 50,000 ‘small molecules’ has identified a potential candidate to inhibit the spread of cancer cells throughout the body. Reported today in the journal Nature Communications, the molecule targets a mechanism of tumour development that had previously been considered ‘undruggable’– in other words, extremely difficult, if not impossible, to target with a drug – and could open the door to further promising new candidates.
A community science initiative – HAEMCODE – has been welcomed for its contribution to our understanding of blood cells and ultimately, to the development of better treatments for leukaemia.
Project will lay foundation for genomic medicine.