The ‘ultimate’ stem cell

29 Oct 2014

In the earliest moments of a mammal’s life, the developing ball of cells formed shortly after fertilisation ‘does as mother says’ – it follows a course that has been pre-programmed in the egg by the mother. Extraordinary as this is, what happens then is even more remarkable.

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Stem cells: master builders, drug testers, immortal elements

01 Oct 2014

Today, we commence a month-long focus on research on stem cells. To begin, Professors Austin Smith and Robin Franklin discuss how Cambridge scientists are helping to provide a stream of new knowledge about how our bodies are made and maintained, and how stem cells can fulfil the promise of being one of medical research’s great hopes.

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Colony of human pluripotent stem cells

Scientists reset human stem cells to earliest developmental state

11 Sep 2014

Scientists have successfully ‘reset’ human pluripotent stem cells to the earliest developmental state – equivalent to cells found in an embryo before it implants in the womb (7-9 days old). These ‘pristine’ stem cells may mark the true starting point for human development, but have until now been impossible to replicate in the lab.

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Rewiring stem cells

09 Jan 2014

A new technique for determining what causes stem cells to convert into other cell types could revolutionise our understanding of how genes function.

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