Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

29 Nov 2016

Researchers from the Wellcome Trust Sanger Institute and the University of Cambridge have created sOPTiKO, a more efficient and enhanced inducible CRISPR genome editing platform. Today, in the journal Development, they describe how the freely available single-step system works in every cell in the body and at every stage of development. This new approach will aid researchers in developmental biology, tissue regeneration and cancer.

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Dish Life: a Cambridge Shorts film

21 Nov 2016

Science is demanding as well as exciting. Dish Life, the final of four Cambridge Shorts films, compares the task of raising stem cells in the lab to the challenge of looking after a gang of unruly kids. In conversation with real-life children, scientists show how tricky it is to work with these ‘super cells’.

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Talk with Your Hands: a Cambridge Shorts film

18 Nov 2016

The capacity for language is what sets us apart from other animals. Talk with Your Hands, the third of four Cambridge Shorts films, explores the richness of sensory perception in interviews with blind and deaf people together with insights from neuroscientists.  

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Anatomy of a decision: mapping early development

06 Jul 2016

In the first genome-scale experiment of its kind, researchers have gained new insights into how a mouse embryo first begins to transform from a ball of unfocussed cells into a small, structured entity. Published in Nature, the single-cell genomics study was led by the European Bioinformatics Institute (EMBL-EBI) and the University of Cambridge.

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Stem cells likely to be safe for use in regenerative medicine, study confirms

18 Dec 2015

Cambridge researchers have found the strongest evidence to date that human pluripotent stem cells – cells that can give rise to all tissues of the body – will develop normally once transplanted into an embryo. The findings, published today in the journal Cell Stem Cell, could have important implications for regenerative medicine.

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Vitamin D could repair nerve damage in multiple sclerosis, study suggests

07 Dec 2015

A protein activated by vitamin D could be involved in repairing damage to myelin in people with multiple sclerosis (MS), according to new research from the University of Cambridge. The study, published today in the Journal of Cell Biology, offers significant evidence that vitamin D could be a possible treatment for MS in the future.

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