Wash cycle: making organs fit for transplantation

20 Jul 2016

There’s a nationwide shortage of suitable organs for transplanting – but what if some of those organs deemed ‘unsuitable’ could be rejuvenated? Researchers at Addenbrooke’s Hospital have managed just that – and last year gave two patients an unexpected Christmas present.

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Time travelling to the mother tongue

19 Jul 2016

T
he sounds of languages that died thousands of years ago have been brought to life again through technology that uses statistics in a revolutionary new way.



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Obesity linked to premature death, with greatest effect in men

14 Jul 2016

A study of 3.9 million adults published today in The Lancet has found that being overweight or obese is associated with an increased risk of premature death. The risks of coronary heart disease, stroke, respiratory disease and cancer are all increased. Overall, the excess risk of premature death (before age 70) among those who are overweight or obese is about three times as great in men as in women.

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Missing link in epigenetics could explain conundrum of disease inheritance

07 Jul 2016

The process by which a mother’s diet during pregnancy can permanently affect her offspring’s attributes, such as weight, could be strongly influenced by genetic variation in an unexpected part of the genome, according to research published today. The discovery could shed light on why many human genetic studies have previously not been able to fully explain how certain diseases, such as type 2 diabetes and obesity, are inherited.

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Anatomy of a decision: mapping early development

06 Jul 2016

In the first genome-scale experiment of its kind, researchers have gained new insights into how a mouse embryo first begins to transform from a ball of unfocussed cells into a small, structured entity. Published in Nature, the single-cell genomics study was led by the European Bioinformatics Institute (EMBL-EBI) and the University of Cambridge.

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