When a drug fails late on in clinical trials it’s a major setback for launching new medicines. It can cost millions, even billions, of research and development funds. Now, an ‘adaptive’ approach to clinical trials and a genetic tool for predicting success are increasing the odds of picking a winner.
Family history and location of genetic fault affect risk for carriers of key breast and ovarian cancer genes20 Jun 2017
A large scale study of women carrying faults in important cancer genes should enable doctors to provide better advice and counselling for treatments and lifestyle changes aimed at reducing this risk.
Women living in the most deprived areas are over 60% more likely to have anxiety as women living in richer areas. However, whether men lived in poorer or richer areas made very little difference to their anxiety levels, according to new research from the University of Cambridge.
Public attitudes towards end-of-life care in progressive neurological illness are conflicted, study reveals05 Apr 2017
Public attitudes in UK and USA reveal support both for life-sustaining interventions and for measures to enable peaceful death in progressive neurological illness such as dementia, according to a survey carried out by researchers at the University of Cambridge.
A genetic trawl through the DNA of almost 100,000 people, including 17,000 patients with the most common type of ovarian cancer, has identified 12 new genetic variants that increase risk of developing the disease and confirmed the association of 18 of the previously published variants.
Moderate drinking is associated with a lower risk of several, but not all, cardiovascular diseases, according to a large study of UK adults led by researchers at the University of Cambridge and University College London published today in The BMJ.
Should screening for heart disease be universal or targeted to those at greatest risk? Ellie Paige (Department of Public Health and Primary Care) weighs up the evidence for The Conversation.
Worries over wasting their doctor’s time, particularly at a time when NHS resources are stretched, may influence when and whether patients choose to see their GP, according to a study carried out by the University of Cambridge.
Researchers in Cambridge are set to receive a £5m Cancer Research UK’s Catalyst Award to improve the early detection of cancers in GP surgeries. The CanTest team, led by Dr Fiona Walter from the University of Cambridge, will work with researchers in three UK sites and across the globe on a five year project that will help GPs to detect cancers in a primary care setting, enabling patients to benefit from innovative approaches and new technologies, and reducing the burden of referrals.
Healthcare is a complex beast and too often problems arise that can put patients’ health – and in some cases, lives – at risk. A collaboration between the Cambridge Centre for Health Services Research and the Department of Engineering hopes to get to the bottom of what’s going wrong – and to offer new ways of solving the problems.